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Cortical Architecture Imaging and Discovery

The CAID (cortical architecture imaging and discovery) lab's research mainly focuses on the discovery of structural and functional architectures of the cerebral cortex via brain imaging and computational modeling. Our long-term goals are to discover the fundamental principles that sculpt the cerebral cortex from organizational, developmental and evolutionary perspectives, and to understand the relationship between cortical structure and function. We are interested in the cortical folding mechanisms, cortical structural connectivity and connectomes, higher-order cortical functional interactions, temporal and frequency dynamics of brain functions, and functional interaction of perception, cognition and environments. We mainly use multi-scale, multi-modal imaging data as the information source, and use a wide range of computational approaches to build models and develop theories. We have strong interests in applying the discovered principles and theories to better understand the dysfunctions of neurological, psychiatric, neurodevelopmental and neurodegenerative disorders including Alzheimer's disease, Schizophrenia, Prenatal Cocaine Exposure, Post-traumatic Stress Disorder, Autism, and Depression, among other brain conditions.

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